Monday, November 12, 2012

Bacterium's immune system is revealed and helps to solve the difficult problem of drug resistance secretly

Bacterium's immune system is revealed and helps to solve the difficult problem of drug resistance secretly
University and gram, Denis of Danish, Lavalle of Canada, one researcher of company reveal the intersection of bacterium and secret of immune system, this discovery may solve some bacteria the difficult problem against nature emerges to antibiotic. This research is issued on November 4 >On the magazine .
Moet exert the research group that Professor lead find by the intersection of Lavalle and the intersection of university and biochemistry, microbiolody and biological the intersection of information and the intersection of department and the west, chosen the particular other source DNA ' DNA) And the passage imbeds it to the particular area of bacterium's genome, these passages can be regarded as a kind of immune factor, resist DNA cleavage to invade. This kind of technology is known as CRISPR/Cas technology again.
Researchers utilize the plasmid - -One can prove this mechanism with the intersection of bacterium and DNA exchanged to go on. In the experiment, the plasmid that researchers will loaded with the antibiotic resisting gene is injected into having a liking for in the hot streptococcus. Some of bacterium contain person who resist bit of DNA of gene combine, arrive in the genome their. The subsequent experiment finds, these bacteria do not accept the characteristic that the plasmid imbeds again. Moet exerts thinking, this indicates these bacteria have obtained immune ability of the antagonistic gene. This kind of phenomenon can explain too why some bacteria can develop and appear and is able to bear medicines, the other bacterium is not able to bear nature .
CRISPR/Cas immune mechanism can also prevent the phage from polluting. Moet exert think discovery this and the biological technical industry will be very much beneficial to food industry, antibiotic industry, because the phage pollutes the economic cost that will increase these trades greatly. (He stands erect )
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