Erythromycin should not be taken immediately after a meal

Erythromycin should not be taken immediately after a meal
Taking the serious one of erythromycin can cause gastric ulcer and gastrorrhagia, so the doctor's order is " taken after a meal " .
Some people misunderstand " Take after a meal " Meaning once putting down the rice bowl take erythromycin. Hardly realize, full to take medicine immediately after the meal, the food wastes a lot of in the stomach, the medicine can't enter the small intestine through stomach fast. Behind a slice of oral administration of erythromycin enters the stomach, disintegrate first, and then dissolve, will enter the small intestine to absorb.
As everyone knows, position that human body absorb, mainly in small intestine, because small intestinal villus old in regional area and blood flow volume abundant and and medicine solubility getting kind in small intestine. Time that take medicine and have a meal have, stress very much successively, the intersection of diet and state, the intersection of acid and alkalinity, the intersection of stomach and the intersection of content and property of thing, can all influence the full play of the drug effect.
Oral erythromycin tablet is erythromycin alkali sugar-coat one, amber second erythromycin and tasteless erythromycin and three kinds. Erythromycin should be taken after meals while taking orally, but does not obey immediately after a meal, must guard against taking on an empty stomach, because take medicines to contact with the mucous membrane of stomach directly on an empty stomach, it is apt to cause gastric ulcer and gastrorrhagia.
The medicine can be diluted by the food while taking after meals, thus reduce the gastrointestinal bad stimulus. Should generally obey to take after meals in 1- 2 hours after the meal, because the stomach has already been emptied mostly at this moment, but there is a small amount of food, such erythromycin is diluted partly, has already relaxed the stimulus to the mucous membrane of stomach, can make erythromycin enter the small intestine comparatively fast and is absorbed.
Modern pharmacology thinks, it has the following danger to take erythromycin promptly after the meal that full:
Full after the meal the food reduces the speed of emptying of the stomach, has lengthened the residence time in the stomach of medicine, fail after increasing the resolving in the stomach of erythromycin;
Full after the meal the food hinders the normal absorption of erythromycin, because the food has on erythromycin molecule absorbing, chela that shuts function, this has reduced the absorption of erythromycin too;
When protein and erythromycin in the food coexists, can oxidize into bisulphide, thus reduce the curative effect of erythromycin.
Talk about the attentive matters taken finally. The erythromycin medicine is time reliance type antibiotic, and their half-life is generally relatively short, if erythromycin 1.5- 2 hours in half-life in block, so it is very fast to excrete. For make in the blood its keeping effective the intersection of sterilization and density, should every take medicine once a hour, namely 3- 4 times day. Erythromycin slice answer whole take, can't break with hand into two with one's hands, either can't chew, otherwise erythromycin enter behind the stomach dissolving out immediately, it is apt to cause gastric ulcer and gastrorrhagia. For another example erythromycin injects powder, the original regulation is dissolved with 5% of the glucose liquid, after employing and injecting water to dissolve on a small quantity now, pour into 200 ml of physiological saline again, the vein is instilled immediately.In daily life, we have many bad habits and customs, accumulating over a long period must endanger the health of the body. Don't think these small habits were worth mentioning, the health care should be set about from trifling matters of everyday life.Please enter while understanding healthy life style:Channel of health careThe editor recommends:Is your life style healthy'the editor recommends:Often drink the draught water, how is it to the health?
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