The new challenge particle albumen floor of medical experience of nanometer can be degraded by the human body

The new challenge particle albumen floor of medical experience of nanometer can be degraded by the human body
It is a research focus in recent years that nanotechnology is applied in medical field, especially transmit the nanometer particle as a medicine the tool receives much concern. But the latest research of the British scientist reveals, the bionic nanometer particle is behind entering human cells, the albumen floor that his top layer adheres to will be degraded by cathepsin L. The relevant research results are issued in 9 Of moon 22>On the periodical.
Utilize the nanometer particle to treat and deliver into cell with the albumen molecule, it is the one of the very promising application in medical field nanotechnology. Nanometer particle often can cover one the intersection of member and the intersection of table and layer, it is usually protein, in order to determine the nanometer particle enters function behind cells . And the researchers of British Liverpool University confirm through studying, in a lot of cells, the intersection of nanometer and the intersection of particle and body will enter nuclear, and the intersection of cathepsin and L of body will degrade the intersection of nanometer and essential the intersection of albumen and layer that is wrap up in outside the particle in being nuclear.
One of the author of this thesis, the doctor says that the linking that in fields lying fallow in rotation of Liverpool University has a match, it is very promising application to use nanometer particle as the medicine and transmit tools, but should make such a biological treatment effective, the particle skin albumen will keep highly intact soon, but the degradation of cathepsin L will cause the drug effect to weaken.
This discovery undoubtedly employs researching and proposing the new challenge to current nanotechnology medical science, mean considering the degradation of cathepsin L in designs of nanometer component in any cell in the future, enable it body wind too nuclear, during design, make it have, inhibit the composition of protease. The person who studies seat of honor of this research project, Raphael Dr. Leavey of Liverpool University says, they can measure the positions and states of the nanometer particle fast, in a large amount now, this contributes to realization of the goal.
As to this a discovery, the biotechnology of Britain of the research of the subsidy and CEO Professor Douglas and Kehl of the bioscience research committee comments: " Nanotechnology is a kind of very attractive technology, may know and promote the development of various technology, some application in biological field of its has already shown very good development prospect, utilize nanotechnology lead, treat protein and DNA, get particular position so as to treat tumour. And for example the basic research which Liverpool University carries on, contribute to promoting medical science of nanometer constantly forward, so as to ensure it is really beneficial to human health, guarantee this discipline has a really bright future. "
|