Vitamin C, E prevent _'s prevention and health care of arteriosclerosis
As to " the effective one " ,These vitamins really have a result of preventing arteriosclerosis, but to " the invalid one " Have not prevented function, will cause arteriosclerosis and symptom to worsen instead sometimes.
After arteriosclerosis and symptom begin to worsen, the blood vessel becomes hard to attenuate, it is extremely tall that the blood piece solidified initiates thromboembolism, risk which cause heart disease and cerebral apoplexy.
The reason causing arteriosclerosis to worsen is caused of active oxygen,etc., oxidized and should be surged(Stress) . Malignant cholesterol (LDL cholesterol) After being oxidized, affix to artery blood vessel wall, cause the blood vessel to attenuate, the blood to solidify --This is to produce the course of arteriosclerosis.
Previous the intersection of animal and experiment verify, have strong against oxidizability vitamin C and E can inhibit the intersection of LDL and oxidizing, prevention arteriosclerosis of cholesterol from already.
But in regarding people as the target's clinical trial, went on separately " effectively " , " invalid " With " reaction " Study. Research verifies, do vitamin C and E vary with each individual effectively, depends on " combines globin " circulating the red blood cell in the human body Protein genetic type. Combine the intersection of globin and gene, have 1 type with two kinds of 2 type forms, each combination globin gene has two genes, inherit one respectively from fathers and mothers, combine three kinds of phenotypes: (1/1 type) 1 type gene of 2 , (2/2 type) 2 times 2 type gene ,(1/2 type) 2 type gene of the 1 type gene of 1 and 1 .
The report claims, 1/1 type person (have 2 1 type persons who combine the globin gene) By arteriosclerosis,and vitamins anti-oxidant to 1/2 type (have 1 type with combining 2 typely by globin gene one pieces respectively) With the 2/2 type (have 2 2 type persons who combine the globin gene) Not preventing the result at all, especially the 2/2 type and person suffering from diabetes, taking anti-oxidant vitamin will accelerate arteriosclerosis instead.
The function of combining globin is " The circulatory system of the red blood cell " ,Namely retrieve the red blood cell which finishes the life-span, utilize the iron delivered to the liver to grade again.
Have already confirmed anti-oxidant vitamin is inoperative, there is 2 type person who combines the globin gene at present, it circulate efficiency getting lower slightly, iron in blood is dense,and in blood is iron may for the " the bad element" . Take vitamin C,etc. behind the anti-oxidant vitamin, iron (three oxidize two iron, + Fe3) Reduced, form and oxidize the inferior iron (Fe2 +) in the body ,And it is very strong to oxidize the ability that the inferior iron oxidizes LDL cholesterol, that is to say, because have in 2 type person blood who combines the globin gene the iron is divided more, so form and oxidize the inferior iron in a large amount after taking anti-oxidant vitamin, has accelerated arteriosclerosis instead. But this conclusion is only the data based on that the test that 300 people carry on obtain, the credibility is not high.
America and Europe is launching " HOPE " of the largest scale so far , " HPS " Wait for several the intersection of people and large-scale test of scale Wan, confront with each other result to oxidize vitamin carry on the investigation.
The research group proposes, should use these data tested on a large scale, revise the result, prove the genetic type can influence the result of anti-oxidant vitamin according to different genetic types of combination globin.
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