Vitamin D_ vitamin
It is steroids derivative, belong to lipid-soluble vitamin. Vitamin D relates to calcification of animal's skeleton, so also called calciferol. It has function against rickets, there is more content in liver, milk and egg yolk China of the animal, the most abundant with the content of cod liver oil particularly. Day
But vitamin D plant for two times,Ergota calciferol (D2) With calciferol (D3) of gallbladder . In the vegetable oil or yeast the intersection of Ergota and firm alcohol not included ' 24 - methyl - 22 takes off hydrogen - 7- take off hydrogen cholesterol) ,Can turn into vitamin D2 after the ultraviolet ray is activated. 7 under animal's skin - take off hydrogen cholesterol, shining by the ultraviolet ray can be turned into vitamin D3, so Ergota firm alcohol and 7 take off hydrogen cholesterol former to call vitamin D often. In animal's body, vitamin D2 and D3 in the food can be absorbed in the small intestine, absorbs into the blood by the lymphatic vessel, mainly absorbed by the liver, then store in the adipose tissue or other tissues with abundant fat. Vitamin D in human body D3 mainly, take off hydrogen cholesterol) . So it is one of the main methods to prevent vitamin D and lack to get sun more. Vitamin D2 and D3 is all colourless crystallization, properties are more steady, survivable, no matter vitamin D2 or D3, itself have living beings to be active, they must change a series of supersession in the body in animal, could become and have active material. This transition is mainly that hydroxy taken in the liver and in the kidney reacts, in hydroxy 25 - hydroxy vitamin D3 of liver at first, then become 1 in further hydroxy of kidney, 25 - (OH) 2 - D3, the latter is vitamin D3 in the internal activity form. 1,25 - two hydroxy vitamin D3 has activity (Fig. 11) of calcium, phosphorus supersession of prominent regulation . It promotes absorbing and transshipping, promote the reabsorption to calcium and phosphorus of renal tubule at the same time to phosphorus of mucous membrane of small intestine. In the skeleton, it contributes to the calcification of the new bone, can also promote calcium to be dissociated out by the old bone marrow quality, thus make osseously to bring in constant renewal in, can maintain the equilibrium of blood calcium at the same time. Because 1, 25 - two hydroxy vitamin D3 is changed over to the blood circulation after the kidney is formated, acts on the small intestine, remote target tissues such as renal tubule, the bon tissue,etc., basically accord with the characteristic of hormone, so someone includes vitamin D in the hormone material. Vitamin D has function of regulating calcium, so are needed by the bone and normal development of tooth. Especially great in pregnant woman, baby and teenagers requirement. Vitamin D if at this moment quantity is insufficient, then calcium and phosphorus is lower than the normal value in the blood, will soften the skeleton and deformity: Called rickets on children; Soften disease for being osseous on pregnant woman. A gram of vitamin D is 40000000 international units. Baby, teenagers, pregnant woman and daily requirement of person who feeds milk are 400- 800 units.
Vitamin D was drawn from the cod liver oil at first by the chemist Karl in 1926. It is faint yellow crystal, melts some 115- 118 , insoluble in water, can be soluble in organic solvents such as ether,etc.. Its chemical property is steady, can still keep the biological activity at 200 , but apt to be destroyed by the ultraviolet ray, so, medicine containing vitamin D should be kept in the brown bottle. The physiological function of vitamin D is to help the human body to absorb phosphorus and calcium, it is essential raw materials which make the bone, so lack vitamin D and cause rickets. Relatively abundant in cod liver oil, animal's liver, its content of China of egg yolk. Vitamin D synthetic with get sun, have something to do with in the human body, so healthy illumination appropriate.
The demand of every day: 0.0005 to 0.01 milligrams. 35 grams of Pacific herring's sliced fish, 60 grams of salmons slice, 50 grams of eels or 2 eggs add 150 grams of mushrooms. There are only persons having a rest and lacking, just need volume to take some food or preparation containing vitamin D.
Efficiency: Vitamin D is the engine which forms skeleton and cartilage, can make teeth hard. Very important too to the nerve, and the inhibitory activity on inflammation.
Side effect: Researchers estimate, take in 0.025 grams of harmful to human body vitamin D long-term every day. The consequence that may lead to the fact is: Disgusting, have a headache, kidney stone, amyotrophy, arthritis, arteriosclerosis, hypertension, is poisoned, suffers from diarrhoea, thirsty slightly, the weight is lightened, symptoms such as many urine and urine in night,etc.. Will damage the kidney when being poisoned seriously, make the soft tissue (such as heart, blood vessel, bronchus, stomach, renal tubule) Calcification.
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