Glueing albumen gene mutation of spot and expansion type _'s general knowledge of myocardium disease

Glueing albumen gene mutation of spot and expansion type _'s general knowledge of myocardium disease
Researcher claim, encode, glue the intersection of spot and albumen and lean towards, glue the intersection of spot and gene mutation of albumen, destroy, insert the intersection of round and structure, they and the intersection of actin and connection among the silk of scene, resulting in expanding myocardium disease. Researchers are on the 29th of January> points out, in myocardium cells, glue the spot albumen and lean towards glueing the spot albumen lie and insert the round one and between costamere, this main position transmitted by contractile force. Researcher of Ou hospital call, the reason why choose to glue the spot albumen gene the American plum, because the known its role in heart. It special one in albumen of code, histone this help, resist cell machinery that receive should defy until heart beat for each time. They infer, the gene playing this kind of function in the expanding myocardium disease patient may be defective.
Researcher to 350 person who expand myocardium the intersection of disease and patient glue spot albumen gene 19 show sub the intersection of DNA and array mutation, screen outside. Three are found glueing the individual with only mutation of albumen gene of spot. Study to verify outside the body, on condition that have this kind of sudden change, hand in and unite changing with actin. Researchers claim, besides finding the specific defect inside of this gene, they encode the function of the albumen with the intersection of Germany and one the intersection of laboratory and the intersection of joint study and these kind of gene still. Under the electron microscope, the heart tissue got after a patient transplants reveals, the single heart exists in the associative area specific and unusually in the muscle between cells and cells.
Heart tissue this obvious " unusual, cracks, rupturing type behaves " Cause them think, glue spot albumen gene mutation easy to destroy until heart stand normal situation that should defy in cell of product. Researchers speculate, this mechanism that they find may totally be very general, though not because the same gene one changes suddenly the samely. The expanding myocardium disease patient helps to resist there may be defects in the albumen that machinery should surge.
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