Many attitudes of factor gene of cell have no _'s general knowledge of close relation with acute pancreatitis

Many attitudes of factor gene of cell have no _'s general knowledge of close relation with acute pancreatitis
According to royal hospital of Edinburg of Britain, many attitudes of gene have a little effect on acute pancreatitic patient's condition.
Some cell factors are important mediums which influence the acute pancreatitic condition, they include: Tumour necrosis factor (TNF - ) , lie between plain - the intersection of 1 and (IL-1 - ) in vain And endogenous theirs resists pharmaceuticals short of moneyly, for instance: Lie between the plain receptor and resist pharmaceuticals (IL-1RA) short of moneyly in vain . The secreting the horizontal part of them is determined by the fact that genetic.
In order to define the role in the above-mentioned links of the genetic factor, Powell JJ and colleague have studied TNF of 190 acute pancreatitic patient and 102 healthy volunteers (TNF-308, TNFB) , IL-1 and receptor resist the factor (IL-1RA) short of moneyly Genetic type. Among them after 51 patients recover, adopt the whole blood to train technology, has further analyzed the phenotypes of these three kinds of cell factors.
The result shows, TNF (TNF-308, TNFB) , IL-1 and receptor resist the factor (IL-1RA) short of moneyly Many attitudes of gene have no relevance with the acute pancreatitic condition, the difference does not exist either between acute pancreatitic group and control group in many attitudes of gene; Slightly TNF - 's secretion level recover with the severe patient, ' Namely its phenotype) Similarly, but the severe patient's IL-1 IL-1RA proportion rises notably.
Studies have suggested, the gene secretes horizontal influence not big on the acute pancreatitic patient TNF - ; Compared with it, in the severe acute pancreatitic patient, there is IL-1 and that resists the factor IL-1RA and secretes the out-of-balance phenomenon short of moneyly, whether this relates to genetic factor, wait to further study to fix.
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