Monday, January 28, 2013

Check _'s treatment in the laboratory test of tubercle

Check _'s treatment in the laboratory test of tubercle
Tubercle (sarcoidosis) It is the granulation swollen disease that a kind of multi system many organs are given much trouble. Infringe lung, dual the intersection of side and the intersection of lung and the intersection of door and lymph node, 90% of the above changes with lung at being clinical often, skin and pathological change of eyes secondly, shallow the intersection of table and lymph node, liver, spleen, kidney, bone marrow, nervous system, heart,etc. whole body can be given much trouble nearly. Disease this one limit disease, most good prognosis since, have the tendency to relieve naturally.
First, blood are checked
Activity develop issue can have leucocyte reduce and anaemia, erythrocyte sedimentation rate increase soon. Nearly there is a serum globulin part of about 1/ 2 of patients that increases, the persons who increase with IgG see more, secondly it is IgG, IgM that increase more rarely. The plasma albumin is reduced. Blood calcium increases, the serum uric acid increases, serum alkaline phosphatase increases. Angiotensin invertase of serum (SACE) Activity acute issue increase ' The normal value is 17.6-34u/ml) ,Consult meanings, lie between in vain plainly serum - 2 receptors (IL- 2R) It is plain to lie between solubility in vain- 2 receptors (sIL- 2R) Rise, have comparatively important meaning to diagnosis of tubercle. Also can a1- resist trypsin, dissolve the intersection of fungus and, enzyme? 2- Little globulin '? 2- MG) , serum adenosine desaturase (ADA) , the fiber links albumens(Fn) Wait for, raise, have, consult the meaning while being sure at clinic.
Second, tuberculin test
About 2/ 3 of the tubercle patients test the reactionless or extremely weak response to the skin of 100u tuberculin.
Third, tubercle antigen (Kveim) Test
Organize, make, mix, hang liquid as antigen by 1:10 physiological saline with acute the intersection of tubercle and lymph node or spleen of patient. Fetch, mix, hang the intersection of liquid and 0.1-0.2ml, make intradermal injection, inject appear mauve papule after the 10 day, 4- spread to 3- 8mm 6 weeks later, it is swollen to form the granulation, it is the positive reaction. The skin which excises the positive reaction organizes diagnosis, the positive rate is 75% - 85% Left and right sides. There is 2% - 5% of the false positive reaction. Because without standard antigen, so it is restricted to employ, are eliminated gradually in recent years.
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