Systemic lupus erythematosus " The Chinese data " Issue
At studying the academic meeting in the 16th national rheumatism held in Hunan Changsha on June 16, study, cooperate the group (CSTAR) in China's systemic lupus erythematosus Register the result of study phasedly after releasing epidemiology of China's systemic lupus erythematosus. Will cooperate the intersection of credit and alternate main committee, BJ Union Hospital, person in charge of group and rheumatism of Chinese Medical Association the intersection of rheumatism and immune the intersection of department and Deputy Director little the intersection of peak and Professor say once, the ones that should be worked out " The Chinese data " Have filled in the blank of registered clinical research of systemic lupus erythematosus of our country, as to canvass, accord with of our country the intersection of crowd and systemic the intersection of lupus erythematosus and disease of characteristic, rotate and return further, dangerous factor, scheme of making a diagnosis and giving treatment that pathogenic reason is correlated with prognosis and making the relevant policy,etc. have directive significance.
It is reported, the complicated in mechanism one's own immune disease of classics that systemic lupus erythematosus one kind has illness coming on, involve a plurality of important internal organs of whole body such as the heart, brain, kidney,etc.. At present, global average ill rate 12~39/10 Wan, of our country crowd 30~70/10 Wan in ill rate, second only to black person (100/10 Wan) ,Rank the second in the world.
The once little peak professor introduced, our country did not have epidemiology characteristic materials about the systemic lupus erythematosus Chinese crowd so far, clinical healing solution and guide that use are mostly to consult the foreign data. This research is that the largest many centres of systemic lupus erythematosus in the world, prospective formation study, rely on the national first systemic lupus erythematosus set up in the same term to register in the platform when the line is real, have already collected 2104 cases at present, has covered 30 provinces, districts, hospital of 106 of the first, second and third of the market besides Tibet in our country, also carried on the collection including biological samples such as serum, DNA,etc. at the same time.
The result of study released this time includes, reveal after carrying on the analysis of base-line to 2104 patients, age is 29.2 years old that the systemic lupus erythematosus of our country has illness coming on on average, women's ill rate is male 10.1 times. It firsts publish clinical manifestation to be successively blood system unusual ' 56.1%) , arthritis ( 54.5%) , butterfly appear erythema ' 47.9%) , nephropathy( 47.4%) With generating heat ' 37.8% ) When. Main one's own the intersection of antibody and table include, resist nuclear positive antibody ' 98.1%) , resist the intersection of dsDNA and positive antibody ' 33.2%) When.
The study on 1980 patients reveals, the ill rate of high pressure of relevant lung artery of systemic lupus erythematosus of our country is about 3.9%, pericarditis, pleurisy and it resists RNP to be dangerous factor independently of disease this in antibody; Reveal, the ill rate of pathological change of the quality is about 4.2% that the systemic lupus erythematosus patient amalgamates among the simple lung on 2024 patients, mucous membrane ulcer, serous coat inflammation and renal pathological change are possible dangerous factors.
It is reported, this meeting will be sponsored by the rheumatism credit of Chinese Medical Association, Chinese Medical Association.
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